Lead Scientist - Upstream Process Development

Lead the design and execution of experimental strategies aimed at defining robust bioreactor processes for the production of vectors and proteins in mammalian cells and alternative production platforms that are robust, scalable and suitable for Current Good Manufacturing Production (cGMP) guidelines.   Responsibilities   Develop and optimize cell culture systems.   Rationally scale the mammalian cell culture processes, including transient transfection, clarification of harvested material, and other upstream unit operations.   Design and apply statistical studies to develop, refine, optimize and characterize cell culture and production processes.   Execute experiments and troubleshoot processes and equipment when needed with associate scientists in the lab.   Conduct laboratory studies to enhance manufacturing technologies, capabilities and processes such as media development, bioreactor fed-batch and perfusion process development, optimization and scale-up.   Requirements   Must demonstrate a keen knowledge of experimental design, underlying scientific principles, and the ability to analyze and assess results.   Applicable academic or industrialexperience in mammalian cell culture process development.   Experience with development of cell culture systems for the production of viral vectors or proteins is preferred.   Experience with small or large scale single-use bioreactor operations, and technology transfer to pilot plant and cGMP manufacturing.   Familiarity with development of producer cell lines, bioreactors, culture media development, and perfusion unit operations.   Excellent opportunity to join a leading provider. Bonus potential complemented with 401(k) retirement program, flexible benefits plan (medical, dental, and vision), life insurance and disability income protection, group legal and long-term care benefits, vacation days, and paid holidays.     Please reference #38289278 when responding.Education Requirements: Bachelor DegreeMinimum Experience Requirements: 5-10 yearsJob City Location: La MesaJob State Location: CAJob Country Location: USA WE ARE AN EQUAL OPPORTUNITY EMPLOYER and our employment decisions are made without regard to race, color, religion, age, sex, national origin, handicap, disability or marital status. We reasonably accommodate individuals with handicaps, disabilities and bona fide religious beliefs. Jobs Career Position Hiring. Top 10 Job Site Top 10 Careers Site Molecular BiologistChemical EngineerBiochemistry Biochemist Cell Culture Upstream Fermentation Mammalian Cell Culture cGMP Bioreactors Scientist Senior Scientist Process Development Process Engineer Chemical Engineering Chemical Engineer Mammalian Cell Culture Upstream Process Development Process Scientist Mammalian Cell Culture cGMP Production Scientist Process Development Cell Culture Manufacturing CMC Chemistry Manufacturing And Controls Current Good Manufacturing Practice    DISCLAIMER: We will make every effort to consider applications for all available positions and shall use one or more of the contact methods and addresses indicated in resume or online application. Indicated location may be proximate or may be desirable point of embarkation for paid or unpaid relocation to another venue. Job descriptions may fit single or multiple presently available or anticipated positions and are NOT an offer of employment or contract implied or otherwise. Described compensation is not definite nor precise and may be estimated and approximate and is negotiable depending on market conditions and candidate availability and other factors and is solely at the discretion of employers. Linguistics used herein may use First Person Singular and First Person Plural grammatical person construction for and with the meaning of Third Person Singular and Third Person Plural references. We reserves the right to amend and change responsibilities to meet business and organizational needs as necessary. Response to a specific posting or advertisement may result in consideration for other opportunities and not necessarily the incentive or basis of the response. Nothing herein is or may be considered a promise, guarantee, offer, pledge, agreement, contract, or oath.  If you submit an application or resume which contains your email address, we will use that email address to communicate with you about this and other positions. We use an email quality control service to maintain security and a remove and dead address filter.
Salary Range: $80K - $140K
Minimum Qualification
5 - 7 years

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